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Health and Safety Executive

Designing and operating safe chemical reaction processes

This is a free-to-download, web-friendly version of HSG143

(First edition, published 2000). This version has been adapted for online use from HSE’s current printed version.

You can buy the book at and most good bookshops.

ISBN 978 0 7176 1051 8 Price £12.50

This publication is aimed at small to medium-sized chemical manufacturing companies using batch and semi-batch processes to produce, for example, resins, polymers, dyestuffs, pharmaceuticals and speciality chemicals.

It is aimed at those responsible for the development, design and operation of chemical plant and processes. It explains how to prevent and control the risk of exothermic runaway.

HSE Books

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 Supercritical Fluid Extraction hsg143.pdf Page 001
SUPERCRITICAL CO2 EXTRACTOR FOR SALE: 5L, 10L and 20L - 2,000 psi Complete Supercritical Fluid Extraction System - closed loop. Our systems are made at our fabrication shop in the state of Washington. Systems available: 5L, 10L, 20L, 100L, and larger custom. Typical build time is 2 weeks. This is not a Apeks Supercritical or Waters Supercritical CO2 Fluid Extraction System. We believe it is a better system, since we use 1/2 inch tubing for the CO2 flow, which is 4 times the flow rate of a Apeks, and up to 64 times the flow rate of a Waters system. We believe the result is faster processing time and better yield from increased exposure to CO2 solvent. Perfect for extraction of terpenes, trichomes, and Cannabinoids. Supercritical CO2 Fluid Extraction is a art, and the operator must have experience and training to obtain results. Go to website

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